Chimeric Ply187 endolysin killsStaphylococcus aureusmore effectively than the parental enzyme
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چکیده
منابع مشابه
Intravitreal injection of the chimeric phage endolysin Ply187 protects mice from Staphylococcus aureus endophthalmitis.
The treatment of endophthalmitis is becoming very challenging due to the emergence of multidrug-resistant bacteria. Hence, the development of novel therapeutic alternatives for ocular use is essential. Here, we evaluated the therapeutic potential of Ply187AN-KSH3b, a chimeric phage endolysin derived from the Ply187 prophage, in a mouse model of Staphylococcus aureus endophthalmitis. Our data sh...
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ژورنال
عنوان ژورنال: FEMS Microbiology Letters
سال: 2013
ISSN: 0378-1097
DOI: 10.1111/1574-6968.12104